Cognitive Disorder Associated with Aging.
ALZHEIMER'S DISEASE (AD)
This is the most common type of dementia that typically affects people older than 65 years. It is a problem with the central nervous system; the brain ( Touhy & Jett, 2020). AD can be defined as a slowly progressive neurodegenerative disease characterized by neuritic plaques and neurofibrillary tangles (Figure 1) as a result of amyloid-beta peptide (Aβ) accumulation in the most affected area of the brain, the medial temporal lobe, and neocortical structures. Alois Alzheimer noticed a presence of amyloid plaques and a massive loss of neurons while examining the brain of his first patient that suffered from memory loss and a change of personality before dying and described the condition as a serious disease of the cerebral cortex.
Causes
The exact cause of Alzheimer’s is unknown. It has been well established
that age, gender, and genetics are the most important risk factors. As older
adults age more, they become more at risk for the disease. Women are more
likely than men to have the disease.
Other risk factors include chemical imbalances,
environmental agents, immunological changes, excessive stress, and ethnicity/race.
Environmental agents: certain viruses such as herpes zoster, and herpes simplex,
and toxic metals such as Zinc and copper. Patients who have experienced a traumatic
brain injury (e.g. war veterans) or repeated head trauma (e.g. football
players) may be more at risk for AD and at an earlier age than others. There is
also a high incidence of AD in people who have Down Syndrome.
Common symptoms
One of the first symptoms is short-term memory loss and
difficulty recalling new information, forgetting names, misplacing household
items, denying the presence of symptoms, degenerating impaired cognition, and
problems with judgment. Restlessness may be decreased if the person is taken
for frequent walks. As the disease progresses, the patient loses all cognitive abilities,
is totally unable to communicate, becomes less aware of the environment, and
loses abilities to perform ADLs.
Treatment:
Pharmacological: Currently, there are only two classes of approved drugs to treat AD, including inhibitors to cholinesterase enzyme and antagonists to N-methyl d-aspartate (NMDA), which are effective only in treating the symptoms of AD, but do not cure or prevent the disease (Breijyeh, & Karaman, 2020).
Non-Pharmacological: Behavioral management in a structured
environment, cognitive stimulation, and memory training like the use of interactive
pet therapy to enhance cognitive function for patients with mild to moderate cognitive
impairment.
Orientation and Validation therapy: Reality orientation is usually appropriate for patients with early AD. Always reorient the patients to date, time, place, and thing. As the disease progresses, validation therapy is used whereby the patient’s feelings and concerns are recognized and acknowledged (Ignatavicius et al., 2018).
Specific strategies to promote the individual’s health,
well-being, and quality of life
Encourage family members to provide pictures of family members and close friends with their names on them to help the patient with recognizing them. Families should reminisce with the patient about pleasant experiences from the past and put the picture of the patient in the door room to help the patient locate the room. It is okay for the patients to talk to themselves in a mirror but if frightened by the mirror, it should be removed or covered. It is important to keep environmental distractions and noise to a minimum so patients will not be more confused, anxious, agitated, and/or aggressive. Be gentle and respectful. Tell the person what you are going to do, step by step while you help them bathe or get dressed. Serve meals in a consistent, familiar place and give the person enough time to eat (HHS, 2021). As the disease progresses, altered thought processes affect the ability to perform ADLs. Encourage the person to perform as much self-care as possible and to maintain independence in daily living skills as long as possible.
Local resources/services to help individuals and families
coping with Alzheimer’s
Alzheimer's &
Dementia Resource Center (Non-profit organization).
Location: 1410 Gene St, Winter Park, FL 32789
Contact information: (407) 436-7750
Website: https://adrccares.org/
Resources for Alzheimer's Care
Here are some places that can give you support and advice:
NIA Alzheimer's and Related Dementias Education and Referral
(ADEAR) Center
Email the ADEAR Center
Phone: 1-800-438-4380
References:
Jett, K. (2020). Neurodegenerative disorders. In T.A. Touhy
& K. Jett (Eds.), Ebersole & Hess' Toward healthy aging: Human needs
and nursing responses (10th ed. pp. 371 - 394). Elsevier.







